What to Know About
Prostate Cancer
250,000+
New prostate cancer diagnoses per year in the United States alone.
Prostate cancer is the most diagnosed non-skin cancer in men.1 In recent years, the U.S. has seen about 250,000 to 315,000 new prostate cancer diagnoses per year, with incidence rising by roughly 3% annually since 2014.2
36,000+
Men are expected to die from prostate cancer in the U.S. this year.
Prostate cancer often causes no noticeable symptoms, so screening is commonly used to detect changes before problems arise. An estimated 36,000 men will die from prostate cancer this year.3
1.7x
Higher incidence in African American men than the overall male population.
Of even deeper concern is the disproportionate impact prostate cancer has on the African American community. African American men are more likely to be diagnosed at a younger age, develop more aggressive disease, and have 1.7× higher incidence than the overall male population.
Types of Prostate Cancer
Some prostate cancers are indolent (slow-growing or low-risk) and may never cause symptoms or require treatment. Other prostate cancers are aggressive and more likely to grow, spread, and require treatment to prevent serious health consequences.
A Modern Approach to Prostate Cancer Detection
Identify
Today, prostate cancer detection focuses on identifying aggressive disease while avoiding unnecessary treatment for cancers that are unlikely to impact health or quality of life.
Test
Screening often begins with a PSA (prostate specific antigen) blood test. When PSA results raise concern, additional tools such as The 4Kscore® Test may be used to better understand a patient’s risk before proceeding to biopsy.
Biopsy
A prostate biopsy is considered when the combined information suggests a meaningful risk of clinically significant (aggressive) prostate cancer. Prostate cancer can only be diagnosed with a tissue biopsy.
[1] American Cancer Society. Cancer Facts & Figures 2026. cancer.org. Accessed 2026.
[2] Siegel RL, et al. CA Cancer J Clin. 2024;74:12-49.
[3] American Cancer Society. Key Statistics for Prostate Cancer. cancer.org. Accessed 2026.